![]() This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other. The cookies is used to store the user consent for the cookies in the category "Necessary". The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". The cookie is used to store the user consent for the cookies in the category "Analytics". The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Advertisement". In addition to certain standard Google cookies, reCAPTCHA sets a necessary cookie (_GRECAPTCHA) when executed for the purpose of providing its risk analysis. These cookies ensure basic functionalities and security features of the website, anonymously. Necessary cookies are absolutely essential for the website to function properly. The Oniris device has mm by mm adjustment, allowing you to get used to each adjustment before moving on to the next, and stopping once you find the perfect level of advancement. Thermoplastic devices which require you to take an impression of your teeth and mouth can help with jaw pain, as can devices which offer mm advancement, such as the Oniris MAD. Using the device for the first time and using it for the whole night, may result in discomfort and a bad experience. It is advised that you persevere with the appliance for at least 30 days as it can take this long to become comfortable with it. If you have never worn a MAD before, it is important that you introduce the device slowly and increase the length of time you wear it over several weeks. As a result some Mandibular Advancement Devices can cause jaw pain or tooth movement as well as hypersalivation. Oral appliances have been shown to effectively decrease symptoms of OSA, but there are some side effects which can lead to low compliance rates.Īn oral sleep device or Mandibular Advancement Device (MAD) is designed to move your lower jaw forward so your airway can remain open whilst you sleep. Please note: If you have false, uneven teeth, gum disease or tempro-mandibular joint dysfunction, please consult with your dentist before purchasing a mandibular device. They are the most widely used alternative for treating snoring and mild Sleep Apnoea and are clinically proven to be an effective alternative to CPAP therapy.Ī Mandibular Advancement Devices should not only reduce symptoms, but it also works to strengthen the muscles of the tongue and surrounding mouth muscles. Mandibular Advancement Devices look like mouth guards used in sport but are so much more than that. Creating space in the mouth and throat leads to reduced snoring and better airflow whilst you sleep. The device aims to advance or move the lower jaw and tongue forward, opening up the back of the throat to make breathing easier. A Mandibular Advancement Device (MAD) is designed for tongue-based snorers and those with mild to moderate symptoms of Sleep Apnoea. The mandibular (also known as the mandible) is your jawbone. What is a Mandibular Advancement Device and how does it work? ![]()
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![]() ![]() Press Fn+1 switch to the customized backlight. This list will help you use every key, as well as RK61's functions. (The Caps, Win and Scrlk keys stop flashing) 5. As RK61 is a smaller keyboard, you need to use Fn key combinations to use keys like Page Up / Page Down or to type some characters. Press same key multiple times to change color. Press Fn+11 to start recording the LED lights of backlight (The Caps, Win and Scrlk keys are flashing) 3. No drivers or softwares are required.ĭetails: Specification: - Dimension: 440*182*42mm, 17.4*7.2*1.6inch - Net Weight: 0.9kg - Backlit Lighting Effect: 168 lighting effects - Dynamic Sidelight Rim: 7 lighting effects - Number of Keys: 108 keys - Switch: Blue Switch - Switch Lifespan: >50 million - Actuation Force: 60gf±5gf - Keystroke Travel: 2.0mm - Keycaps: Double-color injection - Connection: Wired USB - USB Cable Length: 1.8m - Voltage: 5V - Current: 200mA Convenient Shortcuts: FN+F1: My Computer FN+F2: Browser FN+F3: Calculator FN+F4: Music FN+F5: Previous FN+F6: Play/Pause FN+F7: Next FN+F8: Stop FN+F9: Search FN+F10: Favorite FN+F11: None FN+F12: Email FN+Win: Win Key Lock/Unlock Fn+Esc: Hold 3 seconds to reset Lighting Effects Shortcuts: Fn+Pause: Global backlight color switch Fn+Del: Switch the dynamic backlight effects (10 dynamic backlight effects) Fn+Ins: Switch the interactive backlight effects (6 interactive backlight effects) Fn+Home: Switch the breathing backlight effects Fn+PgUp: Switch the Stars Backlight / 7-Color Gradient Backlight Fn+PgDn: Switch the dynamic sidelight effects Fn+1: Switch the customized backlight FN+"→": Lighting Effects Speed Up FN+"←": Lighting Effects Speed Down FN+"↑": Lighting Brightness Up FN+"↓": Lighting Brightness Down How to customize the backlight: 1.
![]() ![]() You can choose from five different time zones: Atlantic, Eastern, Central, Mountain, and Pacific. It then automatically detects the local time for you, so you can count on it being accurate no matter where you are. To begin using the Sony Clock Radio, all you have to do is program the clock to your time zone and plug it in. Brightness settings include high, medium, and low. An adjustable brightness control allows you to dim or brighten the display as needed with just the press of a button. You can appreciate the clock’s backlit LCD face that displays large, amber-colored numbers. The Sony ICF-C1 Alarm Clock is a great option for anyone who has vision difficulties. You can even enjoy falling asleep and waking up to your favorite music using the clock’s programmable sleep timer. An additional feature is a built-in, easy-to-operate analog AM/FM tuner that makes finding your favorite station quick and easy. This Sony AM/FM radio automatically adjusts itself during daylight saving time changes to make your life easier. In addition, you don’t have to worry about setting the clock back one hour in the fall or one hour ahead in the springtime. A battery backup feature has you covered during nighttime power outages. Just toss it into your bag and take it along with you on your trips. In addition, it weighs fewer than 2 pounds, making it perfect for your travels. ![]() Measuring at 4 inches high by 4 inches wide, it is ideal for dormitories and small bedrooms. With its cool, contemporary design and smooth, black exterior, the Sony AM/FM radio alarm clock blends in perfectly with any bedroom decor. In addition, this alarm clock has a digital face that makes reading the time on the clock easy. You can then repeat the snooze for up to an hour. When you press the snooze button, the alarm goes off again for you 10 minutes later. You can set the AM/FM radio to your preferred station, so the first thing you can hear in the morning might be your favorite music. The latter option can help you wake up with soft music that slowly increases in volume until you turn it off or hit the snooze button. The versatile Sony Radio Alarm Clock is programmable, allowing you to awaken you quickly with a buzzer or more gently with the gradual awake feature.Technical details > Date indication - Yes Technical details > Audible alarm(s) - Yes Power > Number of batteries supported - 1 Package features > WEE classification - CL109:5: Package features > Tare weight (kg) - 0.089 kg Package features > Plastic (No PET) - 3.00 g Package features > Paper/Pasteboard - 86.00 g Package features > Palette Qty - 378 pc(s) Package features > Packing quantity - 1.00 pc(s) Package features > Gross width (mm) - 117 mm Package features > Gross height (mm) - 115 mm Package features > Gross depth (mm) - 170 mm Loudspeakers > Number of built-in speakers - 1 Loudspeakers - Number of built-in speakers - 1 Product colour: Black, Volume control: Rotary. Radio type: Clock, Supported radio bands: AM, FM, FM band range: 87.5 - 108 MHz. Stay powered up with an included back-up battery Standard, dual alarm or projector model options Gradual wake alarm and extendable snooze Tune in with an FM/AM analogue radio tuner Logistics data - Harmonized System (HS) code - 85271900 Umożliwia łatwe wyszukanie stacji radiowych i radość słuchania ulubionego programu radiowego niezależnie od pory dnia i nocy. Stylowa, prosta konstrukcja z niewieloma przyciskami zapewnia łatwą obsługę. Automatyczne ustawianie czasu przy pierwszym włączeniu, możliwość zachowania ustawień zegara nawet przy braku zasilania. Regulowana jasność ekranu zapewnia czytelność wyświetlacza, a automatyczna zmiana czasu na letni dodatkowo ułatwia obsługę. Delikatne budzenie dzięki rosnącej głośności alarmu i funkcji drzemki z możliwością jej przedłużania. Battery - Number of batteries supported - 1ĭescription - Zegar z radiem AM/FM, funkcją automatycznego ustawiania czasu i zasilaniem zapasowym z baterii- Jedno ustawienie budzenia radiem lub sygnałem dźwiękowym. ![]() ![]() ![]() ![]() And during various sporting seasons, beer specials are also available on weekends. Thursdays and Fridays, Fireside also offers different beer specials. On Wednesday nights, streamers cost only a quarter apiece and specialty, craft and seasonal beers cost only $3. Tuesday is Trivia Night at the bar as well as South Carolina BBQ Night. On Monday, when Buffalo Shrimp cost $2.95 and domestic drafts go for $2, children 12 and under eat free. A lot of that has to do with Vince Visco, our general manager, who tends to think outside the box.”Īs examples, DeGideo cites the nightly breakdown. That’s because our customers love our specials and food. But on weekends, you might have to wait in line. – have worked hard to create a family-oriented restaurant with sports bar.ĭaytime Bar Manager Al DeGideo says, “There’s a tremendous crowd here every night. and his wife, Debbie, and their son, Pete Penna Jr. No doubt about it – since its opening in 2006, Fireside has become one of the most versatile places to enjoy a good game – or a good meal – anywhere in Montgomery County.īut none of the previous establishments pulled it all together as effectively as Fireside. That’s something to be proud of.Īnd it’s not just because the eatery proudly displays T-shirts autographed by popular former Phillies catcher Darren Daulton and former Flyers great John LeClair and has nine TVs on the sports side of the establishment and five on the restaurant side – not to mention a big-screen TV that virtually any patron can see. Better yet, in the April 2010 issue of Philadelphia magazine, Fireside Bar & Grille was named one of the nine Best Spots to Catch a Game throughout the magazine’s coverage area. The first-place winner in Montgomery Newspapers’ Readers’ Choice Awards for Family Dining in 2008, Fireside duplicated that mark in 2009, adding first-place finishes in the categories of Business Lunch, Catering, Cheese steaks, Pizza, Pub Bar, Ribs and Takeout Lunch & Dinner.Īlthough the eatery didn’t sweep the dining categories, it sure seemed that way.įox 29 TV showed up with its cameras rolling six times last year during what the station dubbed “Red October,” named after the Phillies’ latest playoff run. Such is the case with Ambler’s increasingly popular Fireside Bar & Grille. ![]() Although not everyone subscribes to the accuracy of popularity polls, sometimes they really do hit the mark. ![]() ![]() The money – which is the first financial award in a case brought against the pharmacies in a federal court – will be allocated to tackle an opioid crisis in Lake and Trumbull counties, located outside Cleveland.Īttorneys for the counties, who accused the pharmacies of dispensing vast quantities of opioids whilst turning a blind eye to abuse of the drugs – have said they estimate the cost of combatting opioid abuse could run to $3.3 billion.ĬVS, Walmart, and Walgreens have all said they will appeal the ruling, insisting they neither manufactured or marketed opioids, nor distributed them to illegal 'pill mills' and rogue Internet pharmacies that they claim fuelled the epidemic of opioid abuse. Meanwhile, three of the largest pharmacy chains in the US – CVS, Walgreens and Walmart – have been ordered to pay $650 million to two Ohio counties in the wake of a jury trial, which found them culpable of fuelling the opioid crisis last November. The settlement would ban Endo from promoting opioids and require it to hand over millions of documents related to its role in the opioid crisis for publication in a public online archive. Separately, the company also agreed in principle a deal with 34 US states to provide $450 million over a period of ten years, to resolve allegations that the company boosted opioid sales using deceptive marketing practices. In a statement, Endo said its plans would result in a "substantial" reduction in debt and would create voluntary trusts funded with $550 million set aside for "certain opioid claims." ![]() ![]() The Ireland-domiciled company is struggling under the weight of around $8 billion in debt, and has been hamstrung by costs associated with fighting thousands of suits that accuse it of wrongdoing in its marketing and promotion of painkiller Opana ER (oxymorphone), which was withdrawn from the market five years ago, as well as oxycodone-based products Percocet and Endocet.Įndo's slide into bankruptcy follows in the footsteps of Purdue Pharma – which filed in 2019 but is still negotiating opioid settlement and corporate restructuring terms – as well as Mallinckrodt, which emerged from chapter 11 after agreeing a $1.6 billion settlement earlier this year. 'I am proud of all that the Endo team achieved in a very challenging year. Paladin Labs aims to launch Xcopri in Canada in December 2023.Endo International is the latest drugmaker to file for chapter 11 bankruptcy protection in connection with opioid litigation in the US, after agreeing a $6 billion deal with creditors that includes an offer to settle outstanding lawsuits. 25, 2021 /CNW/ - Endo International plc (NASDAQ: ENDP) today reported financial results for the fourth-quarter and full-year ended Decemand introduced 2021 financial guidance. The US Food and Drug Administration (FDA) first approved Xcopri in 2019, followed by a European approval of the drug in 2021 under the name Ontozry. In a 29 June press release, Paladin Labs’ vice-president and general manager Livio Di Francesco said: “Paladin is dedicated to addressing unmet medical needs, and we are proud to achieve this approval-a milestone in epilepsy treatment.” On March 5, 2021, Endo launches QWO ®, the first and only FDA-approved injectable for the treatment of moderate to severe cellulite in the buttocks of adult women. The drug is currently being studied in a Phase III trial (NCT05067634), evaluating its efficacy in children aged two to 17 years. Endo explained that with the acquisition of AMS, the pharmaceutical company would be gaining what it described as promising medical devices and services. Omnibus Hearing Amended Notice of Agenda of Matters Scheduled for Hearing on Octoat 11:00 a.m. based facilities for the biotech companys COVID-19. Furthermore, a Phase II open-label extension trial (NCT01866111) found that, after a 12-month period, 13% to 16% of patients achieved seizure freedom. Initial Case Conference Order signed on Scheduling Initial Case Conference hearing to be held on at 11:00 AM at Courtroom 723 (JLG) Add to Calendar. Endo International Plc has been inching higher since September 25 after an agreement with Novavax to provide manufacturing services in its U.S. Phase III data showed that all patients who took Xcopri saw a decrease in their average drug load with a mean change of 29% (mean drug load = 2.52) and 32% (mean drug load = 2.43) after 12 and 24 months of treatment, respectively. ![]() This was based on efficacy data from the Phase II and III studies. Health Canada accepted the Montreal-headquartered company’s regulatory filings for Xcopri in August 2022. In this deal, SK Biopharmaceuticals received an upfront payment of $20m but remained eligible to receive $21m more from Endo, subject to the achievement of certain development and commercial milestones. SK Biopharmaceuticals and SK Life Science first discovered and developed the drug, but they gave Endo the rights to commercialise the drug in Canada in a 2021 licensing agreement. ![]() |
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